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Cialis, Tadalafil, is recommended for the treatment of erectile dysfunction. For Tadalafil to work effectively, sexual stimulation is needed.
Adults are recommended a dose of 20 mg taken prior to anticipated sexual activity and without regard to food. It can be taken up to 36 hours and as early as 30 minutes prior to sexual activity. Sexual activity may be initiated by patients at different time points relative to dosing in order to determine their own optimal window of responsiveness. The maximum recommended dosage frequency is once per day.
Dosage requirements are not required for the following patients: • elderly patients, • men with impaired renal function, • men with impaired heptic function, and • men with diabetes.
Healthy subjects were given single doses up to 500 mg, and multiple daily doses up to 100 mg were given to patients. Adverse effects were similar to those seen at lower doses.
Standard supportive measures should be adopted as required in cases of overdose. Hemodialysis helped a lot in eliminating Cialis.
Precaution is given for those who are to drive or to operate machinery. Although the frequency of reports of dizziness in placebo and Tadalafil arms in clinical trials was similar, patients whould be aware of how they react to Cialis before driving or operating a machine.
Patients with a known hypersensitivity to tadalafil or to any of the excipients should not be recommended to use Tadalafil. Cialis has shown to augment the hypotensive effects of nitrates in clinical studies. This is thought to result from the combined effects of nitrates and Tadalafil on the nitric oxide pathway Administration of Cialis to patients who are using any form of organic nitrate is therefore contraindicated.
Tadalafil is not indicated for use in women and should not be used by individuals <18 years.